The latest international news, analysis and features on the HIV epidemic from Avert. Share your views and expertise with your peers in the comments box below the articles.
An engineered protein has been developed which has successfully blocked all known strains of HIV-1 and HIV-2 in a lab environment, and SIV (simian immunodeficiency virus) in monkeys. The protein, named eCD4-Ig, has been described as “the broadest and most potent entry inhibitor described so far”, and could form the basis of a vaccine alternative for HIV – either as a long-term preventative drug, or treatment that works to subdue HIV in the body.
In most countries, the local HIV epidemic is still dominated by the strain of HIV which first entered that specific population. There are several different strains of HIV, organised into types, groups and sub-types; however the global mixing of these different strains has so far been slow. New research in PLOS Computational Biology explains that this slow spread is caused by the first comer advantages, making it very difficult for an invasive strain to enter that same population.